Genesis:Region Locked Games
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The following is a list of Genesis/Mega Drive games which will only play on a console of the same region, as they perform a check at boot to determine what region console they are running on. This check can be defeated by some region adapters, a Game Genie, or a region mod.
Much of the research behind this list comes from the region coding page on the Sega Retro wiki.
Japanese Releases
Note that most Japanese games will not physically fit in a Genesis or PAL Mega Drive, so the cartridge shape also acts as a form of regional lockout.
| Title | Publisher | Release Year | Notes |
|---|---|---|---|
| Aa Harimanada | Sega | 1993 | Will not play on US consoles |
| After Burner II | Dempa Micomsoft | 1990 | This game does not have actual region coding, but will not work on US or PAL consoles with TMSS. |
| Alex Kidd: Tenkuu Majou | Sega | 1989 | This game does not have actual region coding, but will not work on US or PAL consoles with TMSS. |
| Ayrton Senna's Super Monaco GP II | Sega | 1992 | Same ROM as the PAL release, will not play on US consoles |
| Bare Knuckle II | Sega | 1993 | Will not play on US consoles, same ROM as the PAL release |
| Bare Knuckle III | Sega | 1994 | Will not play on US consoles |
| Bishoujo Senshi Salior Moon | Ma-Ba | 1994 | |
| Chou Kyuukai Miracle Nine | Sega | 1995 | |
| Columns III | Sega | 1993 | Will not play on US consoles |
| Comix Zone | Sega | 1995 | |
| Contra: The Hard Corps | Konami | 1994 | |
| Crying: Aseimei Sensou | Sega | 1992 | Will not play on US consoles |
| Doraemon: Yume Dorobou to 7 Nin no Gozans | Sega | 1993 | |
| Dragon Ball Z: Buyuu Retsuden | Bandai | 1994 | Will not play on PAL consoles |
| Dynamite Headdy | Sega | 1994 | Will not play on US consoles |
| Eternal Champions | Sega | 1994 | |
| From TV Animation Slam Dunk: Kyougou Makkou Taiketsu! | Bandai | 1995 | |
| Gods | PCM Complete | 1993 | |
| Golden Axe III | Sega | 1993 | Will not play on US consoles |
| Greatest Heavyweights | Sega | 1994 | |
| Gunstar Heroes | Sega | 1993 | Will not play on US consoles |
| The Hybrid Front | Sega | 1994 | Will not play on US consoles |
| J.League Pro Striker | Sega | 1993 | Will not play on US consoles |
| J.League Pro Striker 2 | Sega | 1994 | |
| J.League Pro Striker Kanzenban | Sega | 1993 | |
| Janou Touryuumon | Sega | 1993 | |
| Jurassic Park | Sega | 1993 | |
| Juuouki | Sega | 1988 | This game does not have actual region coding, but will not work on US or PAL consoles with TMSS. |
| Lethal Enforcers | Konami | 1993 | |
| Light Crusader | Sega | 1995 | Will not play on US consoles |
| McDonald's Treasure Land Adventure | Sega | 1993 | Will not play on US consoles |
| Mega Lo Mania | CRI | 1993 | Will not play on PAL consoles |
| Mickey Mania: The Timeless Adventures of Mickey Mouse | Sega | 1995 | Contains an easter egg where the game will detect if the console's region is changed to Japanese at the lockout screen |
| Mickey to Minnie Magical Adventure 2 | Capcom | 1994 | |
| Monster World IV | Sega | 1994 | Will not play on US consoles |
| NBA Jam | Acclaim | 1994 | |
| NFL Football '94 Starring Joe Montana | Sega | 1994 | |
| Osomatsu-kun: Hachamecha Gekijou | Sega | 1988 | This game does not have actual region coding, but will not work on US or PAL consoles with TMSS. |
| OutRunners | Sega | 1994 | |
| Party Quiz Mega Q | Sega | 1993 | Will not play on US consoles |
| Pebble Beach Gold Links | Sega | 1993 | Will not play on US consoles |
| Phantasy Star II: Kaerazaru Toki no Owari ni | Sega | 1989 | This game does not have actual region coding, but will not work on US or PAL consoles with TMSS. |
| Pro Striker Final Stage | Sega | 1995 | |
| Pulseman | Sega | 1994 | |
| Puzzle & Action: Ichidant-R | Sega | 1995 | |
| Puzzle & Action: Tant-R | Sega | 1994 | Will not play on US consoles |
| Ristar | Sega | 1995 | |
| RoboCop vs. The Terminator | Virgin | 1994 | Will not play on PAL consoles |
| Rocket Knight Adventures | Konami | 1993 | |
| Rolling Thunder 2 | Namco | 1991 | The first ever Genesis/Mega Drive game to incorporate region locking |
| Ryuuko no Ken | Sega | 1994 | Will not play on US consoles |
| Samurai Spirits | Sega | 1994 | |
| Shin Souseiki Ragnacenty | Sega | 1994 | Will not play on US consoles |
| Shining Force II: Inishie no Fuuin | Sega | 1993 | Will not play on US consoles |
| Sonic the Hedgehog 3 | Sega | 1994 | |
| Sonic Spinball | Sega | 1993 | |
| Space Harrier II | Sega | 1988 | This game does not have actual region coding, but will not work on US or PAL consoles with TMSS. |
| Sparkster | Konami | 1994 | |
| Speedball 2 | CRI | 1992 | Will not play on PAL consoles |
| The Story of Thor: A Successor of the Light | Sega | 1994 | |
| Super Daisenryaku | Sega | 1989 | This game does not have actual region coding, but will not work on US or PAL consoles with TMSS. |
| Super Monaco GP | Sega | 1990 | Early releases will not play on PAL consoles |
| The Super Shinobi II | Sega | 1993 | Will not play on US consoles |
| Super Street Fighter II: The New Challengers | Capcom | 1994 | |
| Super Thunder Blade | Sega | 1988 | This game does not have actual region coding, but will not work on US or PAL consoles with TMSS. |
| Surging Aura | Sega | 1994 | |
| Teenage Mutant Ninja Turtles: Return of the Shredder | Konami | 1992 | |
| Teenage Mutant Ninja Turtles: Tournament Fighters | Konami | 1993 | |
| Thunder Force IV | Techno Soft | 1992 | |
| ThunderFox | Taito | 1991 | This game is not region locked but will not work properly on PAL consoles |
| Tom & Jerry | Altron | 1994 | |
| Vampire Killer | Konami | 1994 | |
| Virtua Racing | Sega | 1994 | Will not play on US consoles |
| Wonder Boy V: Monster World III | Sega | 1991 | Will not play on PAL consoles |
| Yuu Yuu Hakusho: Makyou Toitsusen | Sega | 1994 |
PAL Releases
| Title | Publisher | Release Year | Notes |
|---|---|---|---|
| Aaahh!!! Real Monsters | Viacom New Media | 1995 | |
| The Adventures of Batman and Robin | Sega | 1995 | |
| The Adventures of Mighty Max | Ocean | 1994 | |
| Aero the Acro-Bat | Sunsoft | 1994 | |
| Aero the Acro-Bat 2 | Sunsoft | 1995 | |
| Alien Soldier | Sega | 1995 | |
| Animaniacs | Konami | 1994 | |
| Art of Fighting | Sega | 1994 | |
| Astérix and the Great Rescue | Sega | 1993 | |
| Astérix and the Power of the Gods | Sega | 1995 | |
| ATP Tour Championship Tennis | Sega | 1995 | |
| Australian Rugby League | Electronic Arts | 1995 | |
| Ayrton Senna's Super Monaco GP II | Sega | 1992 | Same ROM as the JP release, will not work on US consoles |
| Back to the Future III | Image Works | 1992 | |
| Bio-Hazard Battle | Sega | 1992 | Same ROM as the US release, will not work on JP consoles |
| Body Count | Sega | 1994 | |
| Boogerman: A Pick and Flick Adventure | Interplay | 1995 | |
| Brutal: Paws of Fury | GameTek | 1994 | |
| Bubba 'n' Stix | Core Design | 1994 | |
| Bugs Bunny in Double Trouble | Sega | 1996 | |
| Castlevania: The New Generation | Konami | 1994 | |
| The Chaos Engine | MicroProse | 1994 | |
| Cheese Cat-Astrophe Starring Speedy Gonzales | Sega | 1995 | |
| ClayFighter | Interplay | 1995 | |
| Comix Zone | Sega | 1995 | |
| Cool Spot | Virgin | 1993 | |
| Daze Before Christmas | Sunsoft | 1994 | |
| Dino Dini's Soccer | Virgin | 1994 | Displays a lockout message when the player goes past the main menu |
| Disney's Aladdin | Sega | 1993 | |
| Donald in Maui Mallard | Disney Interactive | 1995 | |
| Dr. Robotnik's Mean Bean Machine | Sega | 1993 | |
| Dragon: The Bruce Lee Story | Virgin | 1994 | |
| Dune II: Battle for Arrakis | Virgin | 1994 | |
| Earthworm Jim | Virgin | 1994 | |
| Earthworm Jim 2 | Virgin | 1995 | Will not work on JP consoles |
| Ecco: The Tides of Time | Sega | 1994 | |
| Elitserien 95 | Electronic Arts | 1994 | |
| Elitserien 96 | Electronic Arts | 1995 | |
| Eternal Champions | Sega | 1994 | |
| Exo Squad | Virgin | 1995 | |
| FIFA Road to World Cup 98 | Electronic Arts | 1997 | |
| Fun 'n' Games | Sony Electronic Publishing | 1994 | |
| Gods | Accolade | 1993 | Will not work on JP consoles |
| Global Gladiators | Virgin | 1993 | |
| Greatest Heavyweights | Sega | 1994 | |
| Gunstar Heroes | Sega | 1993 | |
| Hyper Dunk: The Playoff Edition | Konami | 1994 | |
| Jimmy White's Whirlwind Snooker | Virgin | 1994 | |
| The Jungle Book | Virgin | 1994 | |
| Jurassic Park | Sega | 1993 | |
| Kick Off 3: European Challenge | VIC Tokai | 1994 | |
| Landstalker | Sega | 1993 | |
| Lemmings | Sega | 1992 | This game is not region locked but does not function properly on NTSC systems |
| Lemmings 2: The Tribes | Psygnosis | 1994 | |
| Lethal Enforcers | Konami | 1993 | |
| Lethal Enforcers II: Gun Fighters | Konami | 1994 | |
| Light Crusader | Sega | 1995 | |
| The Lost Vikings | Virgin | 1994 | |
| Marsupilami | Sega | 1995 | |
| Mazin Wars | Sega | 1993 | |
| McDonald's Treasure Land Adventure | Sega | 1993 | |
| Mega Lo Mania | Virgin | 1993 | Early releases are region locked, later ones are not |
| Mega Man: The Wily Wars | Capcom | 1994 | Despite being region locked for PAL consoles, it was not optimized for 50 Hz and runs slower than intended |
| Mega SWIV | Time Warner Interactive | 1995 | |
| Mega Turrican | Sony Electronic Publishing | 1994 | |
| Mighty Morphin Power Rangers | Sega | 1994 | |
| Mighty Morphin Power Rangers: The Movie | Sega | 1995 | |
| Mortal Kombat 3 | Acclaim | 1995 | |
| Muhammad Ali Heavyweight Boxing | Virgin | 1993 | |
| NBA Hang Time | Midway | 1997 | |
| NBA Jam | Arena Entertainment | 1994 | Some releases will not work on JP consoles |
| Nigel Mansell's World Championship Racing | Konami | 1994 | |
| The Ooze | Sega | 1995 | |
| The Ottifants | Sega | 1993 | |
| OutRun 2019 | Sega | 1993 | |
| Pac-Attack | Namco | 1995 | |
| The Pagemaster | Fox Interactive | 1994 | |
| Pebble Beach Golf Links | Sega | 1994 | |
| Phantasy Star IV | Sega | 1995 | |
| Phantom 2040 | Viacom New Media | 1995 | |
| Pinocchio | Sega | 1996 | |
| Probotector | Konami | 1994 | |
| Pocahontas | Disney Interactive | 1996 | |
| Premier Manager 97 | Sega | 1996 | |
| Prince of Persia | Domark | 1994 | |
| The Punisher | Capcom | 1995 | |
| Radical Rex | Sony Electronic Publishing | 1994 | |
| Ranger-X | Sega | 1993 | |
| The Ren & Stimpy Show: Stimpy's Invention | Sega | 1994 | |
| RoboCop vs. The Terminator | Virgin | 1993 | |
| Rock n' Roll Racing | Interplay | 1994 | |
| Rocket Knight Adventures | Konami | 1993 | |
| Samurai Shodown | Sega | 1995 | |
| Saturday Night Slam Masters | Capcom | 1994 | |
| Les Schtroumpfs Autour de Monde | Infogrames | 1996 | |
| Sega Sports 1 | Sega | 1995 | |
| Sensible Soccer | Sony Imagesoft | 1993 | |
| Sensible Soccer: International Edition | Sony Electronic Publishing | 1994 | |
| Shining Force | Sega | 1993 | |
| Shining Force II | Sega | 1994 | |
| Shinobi III: Return of the Ninja Master | Sega | 1993 | |
| Skeleton Krew | Core Design | 1995 | |
| The Smurfs | Infogrames | 1995 | |
| Soleil | Sega | 1995 | |
| Sonic 3 | Sega | 1994 | |
| Sonic Compilation | Sega | 1995 | |
| Sonic the Hedgehog Spinball | Sega | 1993 | |
| Sparkster | Konami | 1994 | |
| Spirou | Infogrames | 1995 | |
| Star Trek: Deep Space Nine: Crossroads of Time | Playmates Interactive | 1995 | |
| The Story of Thor: A Successor of the Light | Sega | 1995 | |
| Street Fighter II': Special Champion Edition | Sega | 1993 | |
| Streets of Rage II | Sega | 1993 | Same ROM as the JP release, will not work on US consoles |
| Streets of Rage 3 | Sega | 1994 | |
| Striker | Sega | 1995 | |
| Sub-Terrania | Sega | 1994 | |
| Sunset Riders | Konami | 1993 | |
| Super Skidmarks | Codemasters | 1995 | This game is not region locked but crashes on NTSC systems when a race begins |
| Super Street Fighter II: The New Challengers | Capcom | 1994 | |
| Superman: The Man of Steel | Virgin | 1992 | |
| Teenage Mutant Hero Turtles: The Hyperstone Heist | Konami | 1993 | |
| Teenage Mutant Hero Turtles: Tournament Fighters | Konami | 1993 | |
| Thunder Force IV | Sega | 1992 | |
| Tintin in Tibet | Infogrames | 1996 | |
| Tiny Toon Adventures: ACME All-Stars | Konami | 1994 | |
| Tiny Toon Adventures: Buster's Hidden Treasure | Konami | 1993 | |
| ToeJam & Earl in Panic on Funktron | Sega | 1994 | |
| Total Football | Domark | 1995 | |
| Toy Story | Disney Interactive | 1996 | |
| Two Tribes: Populous II | Virgin | 1993 | |
| Ultimate Mortal Kombat 3 | Acclaim | 1996 | |
| Ultimate Soccer | Sega | 1993 | |
| Virtua Racing | Sega | 1994 | |
| World Championship Soccer II | Sega | 1994 | |
| Worms | Ocean | 1996 | |
| X-Men | Sega | 1993 | |
| Xenon 2: Megablast | Image Works | 1992 | |
| Zero the Kamikaze Squirrel | Sunsoft | 1995 | |
| Zombies | Konami | 1994 | |
| Zool | Electronic Arts | 1994 | |
| Zoop | Viacom New Media | 1995 |
US Releases
| Title | Publisher | Release Year | Notes |
|---|---|---|---|
| 3 Ninjas Kick Back | Sony Imagesoft | 1994 | |
| 6-Pak | Sega | 1995 | |
| The Adventures of Batman and Robin | Sega | 1995 | Will not work on PAL consoles |
| The Adventures of Mighty Max | Ocean | 1995 | Will not work on PAL consoles |
| Aero the Acro-Bat | Sunsoft | 1993 | |
| Aero the Acro-Bat 2 | Sunsoft | 1995 | |
| Aerobiz Supersonic | Koei | 1994 | |
| Animaniacs | Konami | 1994 | Will not work on PAL consoles |
| Art of Fighting | Sega | 1994 | |
| Astérix and the Great Rescue | Sega | 1994 | |
| ATP Tour Championship Tennis | Sega | 1995 | |
| Ayrton Senna's Super Monaco GP II | Sega | 1992 | |
| Back to the Future III | Arena Entertainment | 1992 | Will not work on PAL consoles |
| Barney's Hide & Seek Game | Sega | 1993 | |
| Bass Masters Classic | Black Pearl Software | 1995 | |
| Beauty and the Beast: Belle's Quest | Sunsoft | 1993 | |
| Beauty and the Beast: Roar of the Beast | Sunsoft | 1993 | |
| The Berenstain Bears' Camping Adventure | Sega | 1994 | |
| Beyond Oasis | Sega | 1995 | |
| Bill Walsh College Football '95 | Electronic Arts | 1994 | |
| Bio-Hazard Battle | Sega | 1992 | Same ROM as the PAL release, will not work on JP consoles |
| Boogerman: A Pick and Flick Adventure | Interplay | 1994 | |
| Boxing Legends of the Ring | American Softworks | 1994 | Only the Mexican release by American Softworks is region locked, the normal US release is not |
| Brutal: Paws of Fury | GameTek | 1994 | |
| Bubba 'n' Stix | Core Design | 1994 | |
| Bubble and Squeak | Sunsoft | 1994 | |
| Bugs Bunny in Double Trouble | Sega | 1996 | |
| Castlevania: Bloodlines | Konami | 1994 | |
| ClayFighter | Interplay | 1994 | |
| Coack K College Basketball | Electronic Arts | 1995 | |
| College Football USA 96 | Electronic Arts | 1995 | |
| College Football USA 97 | Electronic Arts | 1996 | |
| College Football's National Championship | Sega | 1994 | |
| College Slam | Acclaim | 1996 | |
| Columns III: Revenge of Columns | VIC Tokai | 1994 | |
| Comix Zone | Sega | 1995 | |
| Contra: Hard Corps | Konami | 1994 | Will not play on PAL consoles |
| Cool Spot | Virgin | 1993 | Will not play on PAL consoles |
| Crusader of Centy | Atlus | 1995 | |
| Crystal's Pony Tale | Sega | 1994 | |
| The Death and Return of Superman | Sunsoft | 1995 | |
| A Dinosaur's Tale | Hi-Tech Entertainment | 1993 | |
| Dinosaurs for Hire | Sega | 1993 | |
| Disney's Aladdin | Sega | 1993 | |
| Doom Troopers: Mutant Chronicles | Playmates Interactive | 1995 | |
| Double Dragon V: The Shadow Falls | Tradewest | 1994 | |
| Double Dribble: The Playoff Edition | Konami | 1994 | |
| Dr. Robotnik's Mean Bean Machine | Sega | 1993 | |
| Dragon's Fury | Tengen | 1993 | Same ROM as the PAL release, will not work on JP consoles |
| Dragon: The Bruce Lee Story | Acclaim | 1995 | |
| Dune: The Battle for Arrakis | Virgin | 1994 | Will not work on PAL consoles |
| Earthworm Jim | Playmates Interactive | 1994 | |
| Earthworm Jim 2 | Playmates Interactive | 1995 | |
| Ecco: The Tides of Time | Sega | 1994 | |
| ESPN National Hockey Night | Sony Imagesoft | 1994 | |
| ESPN Speedworld | Sony Imagesoft | 1994 | |
| ESPN Sunday Night NFL | Sony Imagesoft | 1994 | |
| Eternal Champions | Sega | 1993 | |
| Exo Squad | Playmates Interactive | 1995 | |
| F-15 Strike Eagle II | MicroProse | 1993 | |
| FIFA 97: Gold Edition | Electronic Arts | 1996 | Same ROM as the PAL release, will not work on JP consoles |
| Flashback: The Quest for Identity | U.S. Gold | 1993 | |
| Frogger | Majesco | 1998 | Will not work on PAL consoles |
| Fun 'n' Games | Tradewest | 1993 | |
| Garfield: Caught in the Act | Sega | 1995 | Same ROM as the PAL release, will not work on JP consoles |
| Gargoyles | Sega | 1995 | |
| Gauntlet IV | Tengen | 1993 | Same ROM as the PAL release, will not work on JP consoles |
| Gods | Mindscape | 1992 | |
| Goofy's Hysterical History Tour | Absolute Entertainment | 1994 | |
| The Great Circus Mystery Starring Mickey & Minnie | Capcom | 1994 | |
| Greatest Heavyweights | Sega | 1993 | |
| Gunstar Heroes | Sega | 1993 | |
| Home Alone 2: Lost in New York | Sega | 1993 | |
| Instruments of Chaos Starring Young Indiana Jones | Sega | 1994 | |
| Jammit | GTE | 1994 | |
| The Jungle Book | Virgin | 1994 | |
| Jurassic Park | Sega | 1993 | |
| Landstalker | Sega | 1993 | |
| Lemmings 2: The Tribes | Psygnosis | 1994 | |
| Lethal Enforcers | Konami | 1993 | |
| Lethal Enforcers II: Gun Fighters | Konami | 1994 | Will not work on PAL consoles |
| Light Crusader | Sega | 1995 | |
| Lightening Force: Quest for the Darkstar | Sega | 1992 | |
| The Lost Vikings | Interplay | 1994 | |
| The Magic School Bus: Space Exploration Game | Sega | 1995 | Will not work on PAL consoles |
| Marko | Domark | 1994 | |
| Marsupilami | Sega | 1996 | |
| Mary Shelley's Frankenstein | Sony Imagesoft | 1994 | |
| Mazin Saga: Mutant Fighter | Sega | 1993 | |
| McDonald's Treasure Land Adventure | Sega | 1993 | |
| Mega Turrican | Data East | 1994 | |
| Mick & Mack as the Global Gladiators | Virgin | 1992 | |
| Mighty Morphin Power Rangers | Sega | 1994 | |
| Mighty Morphin Power Rangers: The Movie | Sega | 1995 | |
| Mortal Kombat 3 | Williams | 1995 | |
| NBA Action '94 | Sega | 1994 | |
| NBA Hang Time | Midway | 1996 | |
| NBA Jam | Arena Entertainment | 1994 | Later releases will not play on JP consoles |
| NBA Showdown '94 | Electronic Arts | 1994 | Same ROM as the PAL release, will not play on JP consoles |
| NCAA Football | Mindscape | 1994 | |
| NFL Football '94 Starring Joe Montana | Sega | 1993 | |
| NHL 98 | Electronic Arts | 1997 | |
| NHL All-Star Hockey '95 | Sega | 1995 | |
| No Escape | Psygnosis | 1994 | |
| The Ooze | Sega | 1995 | Same ROM as the JP release, will not work on PAL consoles |
| OutRun 2019 | Sega | 1993 | |
| OutRunners | Data East | 1994 | |
| Pac-Attack | Namco | 1994 | |
| Pac-Man 2: The New Adventures | Namco | 1993 | |
| The Pagemaster | Fox Interactive | 1994 | Will not go beyond the Sega logo on PAL consoles |
| Pebble Beach Golf Links | Sega | 1994 | |
| Phantasy Star IV | Sega | 1995 | |
| Phantom 2040 | Viacom New Media | 1995 | |
| Pink Goes to Hollywood | TecMagik | 1993 | Same ROM as the PAL release, will not play on JP consoles |
| Pinocchio | THQ | 1996 | |
| Pirates! Gold | MicroProse | 1993 | |
| The Pirates of Dark Water | Sunsoft | 1994 | Some releases have the same ROM as the PAL release, all will not play on JP consoles |
| Pitfall: The Mayan Adventure | Activision | 1994 | |
| Pocahontas | Disney Interactive | 1996 | |
| Prince of Persia | Tengen | 1994 | |
| The Punisher | Capcom | 1995 | |
| Radical Rex | Activision | 1995 | |
| Ranger-X | Sega | 1993 | |
| The Ren & Stimpy Show: Stimpy's Invention | Sega | 1993 | |
| RoboCop vs. The Terminator | Virgin | 1994 | Will not work on PAL consoles |
| Rock n' Roll Racing | Interplay | 1994 | |
| Rocket Knight Adventures | Konami | 1993 | |
| Samurai Shodown | Takara | 1994 | |
| Saturday Night Slam Masters | Capcom | 1994 | |
| Shadowrun | Sega | 1994 | |
| Shanghai II: Dragon's Eye | Activision | 1994 | |
| Shining Force | Sega | 1993 | |
| Shining Force II | Sega | 1994 | |
| Shinobi III: The Return of the Ninja Master | Sega | 1993 | |
| Skeleton Krew | Core Design | 1995 | |
| Soldiers of Fortune | Spectrum HoloByte | 1994 | |
| Sonic the Hedgehog 3 | Sega | 1994 | |
| Sonic the Hedgehog Spinball | Sega | 1993 | |
| Sparkster | Konami | 1994 | Will not work on PAL consoles |
| Speedball 2: Brutal Deluxe | Arena Entertainment | 1991 | Will not work on PAL consoles |
| Spot Goes to Hollywood | Acclaim | 1995 | |
| Star Trek: Deep Space Nine: Crossroads of Time | Playmates Interactive | 1995 | |
| Star Trek: The Next Generation: Echoes from the Past | Sega | 1994 | |
| Street Fighter II': Special Champion Edition | Capcom | 1993 | |
| Streets of Rage 2 | Sega | 1993 | |
| Streets of Rage 3 | Sega | 1994 | |
| Sub-Terrania | Sega | 1994 | |
| Sunset Riders | Konami | 1992 | |
| Superman: The Man of Steel | Sunsoft | 1992 | Will not work on PAL consoles |
| Super Monaco GP | Sega | 1990 | Early releases will not work on PAL consoles |
| Super Monaco GP (Mega Hits Series release) | Sega | 1997 | |
| Super Street Fighter II: The New Challengers | Capcom | 1994 | |
| Tecmo Super Baseball | Tecmo | 1994 | |
| Tecmo Super Hockey | Tecmo | 1995 | |
| Teenage Mutant Ninja Turtles: The Hyperstone Heist | Konami | 1992 | |
| Teenage Mutant Ninja Turtles: Tournament Fighters | Konami | 1993 | |
| ThunderFox | Taito | 1991 | This game is not region locked but will not work properly on PAL consoles |
| The Tick | Fox Interactive | 1994 | |
| Tinhead | Spectrum HoloByte | 1993 | |
| Tiny Toon Adventures: ACME All-Stars | Konami | 1994 | Will not work on PAL consoles |
| Tiny Toon Adventures: Buster's Hidden Treasure | Konami | 1993 | |
| TNN Bass Tournament of Champions | American Softworks | 1994 | |
| TNN Outdoors Bass Tournament '96 | American Softworks | 1996 | |
| ToeJam & Earl in Panic on Funkotron | Sega | 1993 | |
| Top Gear 2 | VIC Tokai | 1994 | |
| Toy Story | Disney Interactive | 1995 | |
| Triple Play: Gold Edition | Electronic Arts | 1996 | |
| Troy Aikman NFL Football | Williams | 1994 | |
| Tyrants: Fight Through Time | Virgin | 1993 | Will not work on PAL consoles |
| Ultimate Mortal Kombat 3 | Williams | 1996 | |
| Virtua Racing | Sega | 1994 | |
| VR Troopers | Sega | 1995 | Same ROM as the PAL release, will not work on JP consoles |
| Weaponlord | Namco | 1995 | |
| Wimbledon Championship Tennis | Sega | 1993 | |
| World Championship Soccer II | Sega | 1994 | Will not work on PAL consoles |
| World Heroes | Sega | 1994 | |
| World of Illusion Starring Mickey Mouse and Donald Duck | Sega | 1992 | |
| World Series Baseball | Sega | 1994 | |
| World Series Baseball '95 | Sega | 1995 | |
| X-Men | Sega | 1993 | |
| X-Perts | Sega | 1996 | Will not work on JP consoles |
| Zero the Kamikaze Squirrel | Sunsoft | 1994 | |
| Zombies Ate My Neighbors | Konami | 1993 | |
| Zoop | Viacom New Media | 1995 |